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Conclusions: NaOCl followed by final EDTA irrigation performed either by syringe needle or the GentleWave^® System caused minimal dentin erosion. 

Conclusions: The GentleWave^® System demonstrated at least four times deeper cleaning in the apical region than currently employed ultrasonic systems.

Conclusions: Results revealed that the GentleWave^® System is effective in retrieving separated instruments while conserving the dentinal structure.

Conclusions: Treatment of sizable periapical lesions with the GentleWave® System resulted in a cumulative healing success rate of 97.7% at 12 months.

Conclusions: When patients were treated with the GentleWave® System, the cumulative success rate of healing was 97.3% at twelve months.

Conclusions: The GentleWave® System showed a significantly greater cleaning capacity and reduction in residual debris within the mesiobuccal and mesiolingual canals of mandibular molars and the mesiobuccal canals of maxillary molars than those cleaned with standard methods.